ICFHR 2008 Main Page




      August 19, 2008


      August 21, 2008






Date: Tuesday August 19, 2008

Time: 9:20 AM


Speaker: Dr. Hans-Leo Teulings, NeuroScript, Tempe, Arizona


Title: Quantification of Medication Side Effects Based on Dynamic Handwriting Features*




Continuous anti-psychotic medication often leads to debilitations such as tardive dyskinesia and parkinsonism in schizophrenia patients. Conventional visual observation scales normally used by an experienced psychiatrist to detect movement side effects could not show significant differences between patients on different dosages or medications. In this presentation, we show that handwriting analysis is able to derive many features that can detect such differences, e.g. normalized jerk (i.e. up or down) of total stroke, relative duration and size of the primary (i.e. ballistic) submovement, relative time to peak vertical velocity of the secondary submovement, number of peak acceleration points, vertical velocity, and peak vertical acceleration, etc.   Results indicated that the dysfluency measures significantly correlated with dosage and type of medication such as risperidone, olanzapine and quetiapine. These results confirm that handwriting movement analysis could help guide psychiatrists when prescribing medication to their patients.


* This presentation is co-authored by Michael P. Caligiuri of the University of California, San Diego.

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